Do the patients we treat with hypolipemic drugs have a coronary risk?

Vilaseca Canais, J.; Buxeda Mestres, C.; Cámara Contreras, C.; Flor Serra, F.; Pérez Guinaldo, R.; Sánchez Viñas, M.

Atencion Primaria 20(1): 49-53

1997


ISSN/ISBN: 0212-6567
PMID: 9303663
Document Number: 473663
To study the appropriateness of lipid-lowering drugs treatment through four methods of calculating coronary risk (CR). Crossover study. Primary care centre. All patients receiving lipid-lowering drugs. CR was determined for individuals with application criteria by four methods: the simplified Framingham, Dundee-Risk-Disk, modified Sheffield label and Cardiovascular Risk in Primary Care (CVRap). 330 patients followed the treatment, 137 men and 193 women with an average age of 58.8 (SD 10.2). 54.2% received statims, 28.5% clofibrates, 13.6% resins and 3.6% other drugs. 186 patients were included, 75 (22.7%) being excluded because of secondary prevention and the rest because they were not the right age or had no cholesterol data prior to treatment. 38.3% were at high CR according to Framingham, 25.6% according to CVRap, 18.7% according to Dundee-Risk-Disk and 16% according to modified Sheffield. Concordance between these methods was adequate. Between 16% and 38.3% of the individuals treated are at high CR. If we also include patients with severe Hypercholesterolaemia and diabetics with Hypercholesterolaemia, this percentage rises to 59.7-73.3%, according to the CR assessment method used.

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