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Effect of controlled hypotension induced by prostaglandin E1 on evoked spinal cord potential and spinal cord blood flow

Ide, R.; Fukusaki, M.; Yamaguchi, K.; Matsumoto, M.; Ogata, K.; Sumikawa, K.

Masui. Japanese Journal of Anesthesiology 46(10): 1342-1346

1997

ISSN/ISBN: 0021-4892
PMID: 9369049
Document Number: 472988
We evaluated the effect of controlled hypotension induced by PGE1 on evoked spinal cord potential (ESCP) and spinal cord blood flow (SCBF) in 14 patients undergoing laminectomy or laminoplasty. They were divided into two groups: hypotensive group (group H), non-hypotensive group (group N). Controlled hypotension was induced with PGE1 to maintain mean arterial blood pressure at 55-60 mmHg for 45 min. The amplitude and latency of the N 1 potential were analyzed, and the SCBF was estimated by laser doppler flowmeter. There were no significant differences in ESCP and SCBF. These results suggest that controlled hypotension by PGE1 maintained normal local spinal cord blood flow autoregulation.

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