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Advances in pancreas transplantation: the University of Wisconsin experience

Odorico, J.S.; Becker, Y.T.; Van der Werf, W.; Collins, B.; D'Alessandro, A.M.; Knechtle, S.J.; Pirsch, J.D.; Sollinger, H.W.

Clinical transplants 1997: 157-166

1997

ISSN/ISBN: 0890-9016
PMID: 9919400
Document Number: 470851
The data show that with careful surgical technique, modern immunosuppression with MMF and FK506, and pancreatic allograft biopsy, it should be possible to achieve: 1) a low rate of technical complications, 2) improved long-term graft survival, particularly in solitary pancreas recipients improving the risk/benefit ratio of this option for nonuremic diabetics, 3) a high safety profile with combined MMF and FK506 immunosuppression, 4) safe transplantation using enteric drainage without increased risk of rejection, infection or graft loss, and 5) successful pancreas transplantation without induction therapy.

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