The need of prolonged BCG treatment in superficial bladder cancer is suggested by the development of a peripheral immune response induced by BCG

Shekarsarai, H.; Zlotta, A.R.; Drowart, A.; Van Vooren, J.P.; De Cock, M.; Pirson, M.; Palfliet, K.; Jurion, F.; Vanonckelen, A.; Simon, J.; Schulman, C.C.; Huygen, K.; Shekarsarai, H; Zlotta, A.R; Drowart, A; Van Vooren, J.P; De Cock, M; Pirson, M; Palfliet, K; Jurion, F; Vanonckelen, A; Simon, J; Schulman, C.C; Huygen, K

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The need of prolonged BCG treatment in superficial bladder cancer is suggested by the development of a peripheral immune response induced by BCG

Shekarsarai, H.; Zlotta, A.R.; Drowart, A.; Van Vooren, J.P.; De Cock, M.; Pirson, M.; Palfliet, K.; Jurion, F.; Vanonckelen, A.; Simon, J.; Schulman, C.C.; Huygen, K.

Acta Urologica Belgica 65(1): 1-4

1997

ISSN/ISBN: 0001-7183

PMID: 9245197

Document Number: 470426

Optimal duration of immunotherapy treatment by BCG for the prevention of recurrences of superficial bladder cancer is still unknown. We have studied the evolution and duration of the cellular immunity response at the peripheral level after BCG intravesical instillations. Our results show that immunity activation after BCG is of short duration and don't take more than 6 months. Our results support, strengthen and partially allow to explain the utility of maintenance treatment by BCG following 6-weekly instillations.