Modification of the DNA spatial structure when complexed with cisplatin
Arutiunina, S.G.; Mamasakhlisov, E.S.; Morozov, V.F.; Dalian, E.B.; Khachikian, R.E.; Vardevanian, P.O.; Orioli, P.; Bruni, B.
Biofizika 42(2): 372-377
1997
ISSN/ISBN: 0006-3029 PMID: 9172682 Document Number: 470142
The experimental and theoretical analyses of the conformational transitions of DNA-cis-platinum complexes have been carried out. It is shown that at low concentrations of the ligand, the thermodynamic parameters of the helix-coil transition of the complexes are not the result of the local B-->A transition.
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