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The Wermer syndrome

Târcoveanu, E.; Strat, V.; Cotea, E.; Filip, V.; Zbranca, E.; Vulpoi, C.; Florea, N.; Daniil, C.; Crumpei, F.; Rusu, V.

Chirurgia 92(4): 257-267

1997

ISSN/ISBN: 1221-9118
PMID: 9445640
Document Number: 469728
The difficult diagnostic and therapeutic management of patients having gastrinoma with multiple endocrine neoplasia type I (MEN I) has been discussed by reference to the literature and a personal experience of 2 patients with Wermer syndrome. The syndrome is often familial and might be inherited as an autosomal dominant trait with a high but variable degree of penetrance. Pancreatic islets, parathyroid glands and adenohypophyseal cells are the three localization main for endocrine involvement in MEN I syndrome.

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