Determination of the potential doubling time of tumors using bromodeoxyuridine and flow cytometry
Schwyn, U.; Kaser-Hotz, B.; Hauser, B.; Fodor, G.; Ruckstuhl, H.; Crompton, N.E.
Schweizer Archiv für Tierheilkunde 139(10): 441-448
1997
ISSN/ISBN: 0036-7281 PMID: 9441381 Document Number: 469500
Tumor growth-rate affects prognosis and treatment planning. The injection of bromodeoxyuridine in dogs and cats permits determination of the potential doubling time following a biopsy of neoplastic tissue and flow cytometric analysis. The essentially non-invasive method gives exact results within 24 hours. This report describes a method to measure potential tumor doubling time of different tumors, and presents results of canine and feline tumors.