End stage liver disease in a 13-year old secondary to hepatitis C and hemochromatosis
Miller, M.; Crippin, J.S.; Klintmalm, G.
American Journal of Gastroenterology 91(7): 1427-1429
1996
ISSN/ISBN: 0002-9270 PMID: 8678008 Document Number: 467824
Hepatic parenchymal iron deposition is a well known complication of chronic hepatic inflammatory states. This can make the differential between chronic hepatitis and hereditary hemochromatosis difficult, however. The case of a 13-yr-old male with chronic hepatitis C and hereditary hemochromatosis resulting in end stage liver disease and the need for orthotopic liver transplantation is described. There has been no previously described case of the coexistence of these two diseases in a pediatric patient, resulting in end stage liver disease. The progression to cirrhosis in a patient of this age suggests a more rapid progression of the combined diseases than with either disease alone.