Early ovarian cancer: value of a negative staging laparotomy
Faught, W.; Lotocki, R.J.; Heywood, M.; Krepart, G.V.
European Journal of Gynaecological Oncology 17(3): 200-203
1996
ISSN/ISBN: 0392-2936 PMID: 8780918 Document Number: 467597
Objective: To assess the risk of recurrence in patients with stage I (negative cytology) epithelial ovarian cancer receiving no adjuvant therapy. Methods: Between 1976 and 1991, 51 patients with apparent stage I ovarian cancer underwent a comprehensive surgical staging that included: peritoneal cytology, omentectomy, pelvic and para-aortic lymphadenectomy, peritoneal biopsies and either unilateral salpingo-oophorectomy or TAH and BSO. Results: Eleven of 51 patients (22%) were found to have stage II or III disease based on a positive staging laparotomy. Thirty seven of 40 patients with stage I disease received no further therapy. There was one recurrence (stage 1C - grade 1) in patients with surgical stage 1C while there were no recurrences in patients with either stage 1A or 1B disease. Conclusion: This study concludes that surgical staging in apparent early stage ovarian cancer can identify a group of patients that require surgical therapy alone.