The search for ways to improve the efficacy of tuberculosis revaccination in children with immunological deficiency

Chernushenko, E.F.; Kadan, L.P.; Kruglova, I.F.; Podgainaia, E.A.

Problemy Tuberkuleza 1: 29-32

1996


ISSN/ISBN: 0032-9533
PMID: 8907482
Document Number: 466675
Clinicoimmunological examination of children to be BCG revaccinated showed 50% of them to have immunodeficiency. Primarily T-cell and macrophagal components of immunity were compromised. The study of immune response to BCG in animals with T-cell and macrophage immunodeficiency validated feasibility of improving antituberculous vaccination efficacy by using thymalin and sodium nucleinate.

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