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A comparative morphological study of homo- and heterotopic neural transplants

Otellin, V.A.; Petrova, E.S.

Morfologiia 109(2): 12-16

1996

ISSN/ISBN: 1026-3543
PMID: 8963409
Document Number: 465277
A comparative study of the development of neocortex embryonal anlage was carried out using light and electron microscopy in 15 days Wistar-line rat embryo after its transplantation into the brain and disturbed sciatic nerve of mature rats. Homotopic transplants contained twice more neurons than heterotopic ones 30 days later. Unlike to intracerebral transplants, in grafts developing in the nerve, there forms a multilayer lining from ependymocytes on the border with recipient tissue. Microenvironment was suggested to influence the realization of the transferred cells precursors histoblastic properties.

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