Pneumonia caused by Saiboku-to
Katsura, H.; Hashimoto, I.; Taira, M.; Kadoriku, C.; Yamawaki, I.
Nihon Kyobu Shikkan Gakkai Zasshi 34(11): 1239-1243
1996
ISSN/ISBN: 0301-1542 PMID: 8976080 Document Number: 465123
A 72-year-old man was being treated with Saiboku-to for throat discomfort. Forty-two days after the start of Saiboku-to therapy, dyspnea and fever developed and he was admitted to the hospital. Arterial blood gas analysis showed arterial hypoxemia, and a chest X-ray film and chest CT scan showed diffuse linear-nodular shadows in both lung fields. The results of a lymphocyte-stimulation test were positive for Saiboku-to and Saiboko-to-induced pneumonia was diagnosed. Saiboku-to was stopped and prednisolone was given. The symptoms, respiratory status and chest X-ray findings markedly improved. To our knowledge, this is the fifth case of Saiboku-to-induced pneumonia reported in Japan.