Noncardiogenic pulmonary edema associated with hydrochlorothiazide use
Saldaña, A.; Jalil, J.; Gaete, P.; Fajuri, A.; Castro, P.; Godoy, I.; Corbalán, R.
Revista Medica de Chile 124(6): 720-724
1996
ISSN/ISBN: 0034-9887 PMID: 9041730 Document Number: 464945
A 54 years old female patient with a mitral valve prolapse and a rheumatoid arthritis treated with steroids was admitted with dyspnea and hypotension, that started 30 min after taking a pill containing enapril and hydrochlorothiazide. Hemodynamic monitoring with a Swan-Ganz catheter showed a pulmonary capillary pressure of 5 mm Hg, a systemic vascular resistance of 887 (dyn sec)/cm5 and a cardiac output of 10 l/min. The patient had a history of adverse reactions to thiazides and responded to volume replacement, dopamine and steroids.