The ecdysteroid fraction of the above-ground portion of Serratula coronata L. in the spontaneous E-rosette formation reaction and the agar migration test in vitro
Trenin, D.S.; Volodin, V.V.; Beĭkin, I.B.; Shlykova, A.B.
Eksperimental'naia i Klinicheskaia Farmakologiia 59(1): 55-57
1996
ISSN/ISBN: 0869-2092 PMID: 8704636 Document Number: 464740
Reaction of E-rosette formation and agar migration test in vitro showed that small concentrations (7.5.10(-13) -7.5.10(-8) M) of phytosteroid ecdysterone (20-hydroxyecdysone) induce the activation of human lymphocytes. The effect of higher concentrations (7.5.10(-7) -7.5.10(-5) M) is less pronounced (two-phase effect).