Triple therapy in duodenal ulcer healing--a follow up study

Qureshi, H.; Ahmed, W.; Zuberi, S.J.

JPMA. Journal of the Pakistan Medical Association 46(9): 194-195

1996


ISSN/ISBN: 0030-9982
PMID: 8936983
Document Number: 464719
Thirty-nine Helicobacter pylori (HP) positive chronic duodenal ulcer patients completed the 4 weeks treatment of triple therapy (Denol, Metronidazole and Amoxil). Of these 29 showed healed duodenal ulcer and negative CLO test at 8 weeks (eradication). They were followed at 3,6 and 12 months and at each follow-up, endoscopy and CLO testing were repeated. At 12 weeks, 54% showed a healed ulcer and negative CLO and these figures reached to 69 and 66% at 6 and 12 months respectively. Thirty percent relapsed within 1 year. The present study indicates a prolonged remission of duodenal ulcer following HP eradication.

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