ACE inhibitors from the viewpoint of the clinical pharmacologist
Hitzenberger, G.
Wiener Medizinische Wochenschrift 146(11): 225-227
1996
ISSN/ISBN: 0043-5341 PMID: 8928519 Document Number: 464343
For treatment of hypertension drugs are desirable which exert a 24 hours lasting blood pressure control. Among the ACE-inhibitors some drugs exist which have this action. The elimination pathway plays a minor role in this respect. Not only the inhibition of Angiotensin II generation but also the decreased inhibition of bradykinin-degeneration plays a crucial role with regard to several endothelial functions controlling the so called remodeling of the cardiovascular system.