Statistical analysis of the genotoxicity study results

Szymczak, W.; Przybojewska, B.

Polish Journal of Occupational Medicine 3(2): 201-207

1990


ISSN/ISBN: 0860-6536
PMID: 2130873
Document Number: 4632
One of the methods used in the genotoxicity study of chemical compounds is micronucleus test in vivo. There is no clear consensus as to which statistical method is most suitable to study the frequency of occurrence of micronucleated polychromatic erythrocytes. This paper proposes two statistical tests: approximate normal test and conditional binomial test (Kastenbaum & Bowman).

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Statistical analysis of the genotoxicity study results