The effect of the dispersity of tegalid on its bioavailability
Lopatina, N.B.; Lebedeva, M.N.; Mikhaĭlitsyn, F.S.; Khalikov, S.S.
Meditsinskaia Parazitologiia i Parazitarnye Bolezni 1: 23-25
1996
ISSN/ISBN: 0025-8326 PMID: 8700005 Document Number: 462994
The impact of the new helminthicide Tegalide, a dibromobenzamide derivative, on its pharmacology was investigated. The agent given as a fine-dispersed form was found to be more intensively absorbed by the body and to be in animals' blood for a longer period of time (MRT fine-dispersed and MVR coarse-dispersed were 88.5 and 50.4 hours, respectively). As the fine-dispersed fraction of Tegalide increased, its bioavailability showed an equivalent increase.