Influence of recirculation type blood cardioplegia on perfusion pressure in open heart surgery
Watanabe, T.; Murase, M.; Yasuura, K.; Matsuura, A.; Maseki, T.; Oohara, Y.; Ito, T.; Sakai, Y.; Miyahara, K.; Yuasa, T.; Kawaratani, Y.; Yamada, T.
Kyobu Geka. Japanese Journal of Thoracic Surgery 49(9): 716-720
1996
ISSN/ISBN: 0021-5252 PMID: 8741449 Document Number: 462744
Infusion blood cardioplegia often decreases the perfusion pressure during open heart surgery. The blood level of bradykinin (BK) was measured in both the cardiopulmonary bypass (CPB) and blood cardioplegia circuit. Infusion cardioplegia with recirculation type circuit increased the BK level of cardioplegia and the perfusion pressure decreased abruptly with the increase BK level in the CPB circuit. In the case of single pass type circuit the BK level was not increased either in cardioplegia or CPB and perfusion pressure was not decreased. We concluded that the single pass type of cardioplegia circuit is superior to the recirculation type because of less production of BK.