Pathophysiology and management of VIPoma: a case study
Meriney, D.K.
Oncology Nursing Forum 23(6): 941
1996
ISSN/ISBN: 0190-535X PMID: 8829164 Document Number: 462270
To review the pathophysiology and clinical treatment of VIPomas, neuroendocrine tumors that secrete vasoactive intestinal polypeptide, and VIPoma syndrome. Published clinical treatments and case studies in the medical literature and case study data from a patient's medical record. VIPomas are rare neuroendocrine tumors that cause a syndrome of life-threatening symptoms. Clinical management is complex, yet little information is available in the medical and nursing literature to guide the clinician. Information about the pathophysiology and management of the disease may facilitate care of these patients. A case study presentation provides an example of the care required by one patient with VIPoma. The nurse has an important role in assessing, educating, and caring for the patient with VIPoma. Interventions include managing complex fluid and electrolyte imbalances, chemotherapy administration and management of side effects, activity and rest alterations, safety issues, altered social roles, and educational needs regarding medications, central lines, and follow-up care.