Pancreatic harvesting from multiorgan donors for islet transplantation
Lo Monte, A.; Maione, C.; Basile, V.; Napoli, N.; Stassi, G.; Todaro, M.; Richiusa, P.; Mattina, A.; Giordano, C.; Galluzzo, A.; Farina, F.; Buscemi, G.; Rapisarda, L.M.
Minerva Chirurgica 51(10): 759-764
1996
ISSN/ISBN: 0026-4733 PMID: 9082202 Document Number: 461640
The result of human islet isolation procedures to transplant in type I insulin-dependent diabetic patients is significantly conditioned by the technique used for pancreas procurement from multiorgan donor. In fact, during multiorgan procurement, an improper handling of the gland could result in edema or degranulation of the acinar tissue, detrimental for the islet purification step. The surgical technique used by our surgical team, includes some important refinements to obtain the largest quantity and the best quality of purified endocrine material.