Cooling shell in renal transplantation. Thermometric evaluation of a prototype
Desgrandchamps, F.; Eugene, M.; Tuchschmid, Y.; Muller, F.; Teillac, P.; Idatte, J.M.; Le Duc, A.
Progres en Urologie Journal de l'Association Francaise d'Urologie et de la Societe Francaise d'Urologie 6(1): 25-29
1996
ISSN/ISBN: 1166-7087 PMID: 8624524 Document Number: 460763
We have developed a cooling system for renal transplants designed to eliminate the second period of warm ischaemia corresponding to the vascular anastomosis phase of renal transplantation. This is an autonomous and independent system which forms a shell around the transplant. Following application of the system, cooling is achieved by refrigeration of a Multitherm sponge contained in the wall of the shell. The thermometric characteristics of a prototype were evaluated in vitro and in vivo in pigs. This system allows the kidney to be preserved at a temperature of less than 10 degrees C for 1 hour without inducing any risk of lesions of the renal surface. Human applications should be developed in the near future.