New therapeutic approach to pancreatic cancer by monoclonal antibodies
Sawada, T.; Chung, Y.S.; Sowa, M.
Gan to Kagaku Ryoho. Cancer and ChemoTherapy 23(12): 1654-1656
1996
ISSN/ISBN: 0385-0684 PMID: 8886037 Document Number: 460358
The prognosis of pancreatic cancer is extremely poor in digestive cancers even with systemic therapy including surgery. Thus development of a new therapeutic approach is awaited. Recently, new trials of cancer treatments using monoclonal antibodies conjugated with anti-cancer drugs or labeled with isotopes have been reported. Here, we discuss the possible therapeutic application for pancreatic cancer of adriamycin-conjugated and 131I-labeled Nd2, which is produced against pancreatic cancer mucin.