Weight of resected liver is positively correlated with serum hHGF level
Miyata, K.; Taniguchi, H.; Takeuchi, K.; Koyama, H.; Tanaka, H.; Takahashi, T.
Hepato-Gastroenterology 43(12): 1589-1593
1996
ISSN/ISBN: 0172-6390 PMID: 8975970 Document Number: 459146
Background/Aims: Human hepatocyte growth factor (hHGF) is involved in the control of liver regeneration. Material and Methods: We measured serum hHGF levels before and after partial hepatectomy in 43 patients and recorded the weight of the resected liver. Results: Serum hHGF levels increased soon after operation and decreased thereafter. In the noncirrhotic group, the maximum hHGF concentration and the area under the curve of hHGF seven days postoperatively correlated with the weight of the resected liver. Conclusion: The amount of injured liver tissue can be approximated by the serum hHGF levels. This calculation can be useful in evaluating cases of hepatectomy, general hepatic injury, liver transplantation, and other types of hepatic damage.