Comparative studies on freeze dryers of one and two chamber systems
Stampf, G.; Tórók, E.
Acta Pharmaceutica Hungarica 66(2): 65-69
1996
ISSN/ISBN: 0001-6659 PMID: 8669279 Document Number: 458672
Authors carried out a comparative study on freeze--dryers of one--and two chamber-systems. Samples containing dextran and mannitol were used for the control of process-uniformity. Moisture content of the products were monitored during the sublimation process and after closing the ampules by colouring of the CoCl2 labelled samples. They put forward proposals for the combined measurement of barometric vapor pressure and product temperature in order to improve safety.