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Effects of polydioxanone and silk on normal cicatrisation of surgically injured myocardial tissue. An experimental model

Serrano-Gallardo, G.; Santibáñez Escobar, F.; Amansio Chassín, O.; Uribe Uribe, N.; Rojero Vallejo, J.; Olvera Nevárez, R.

Archivos del Instituto de Cardiologia de Mexico 66(1): 23-28

1996

ISSN/ISBN: 0020-3785
PMID: 8768618
Document Number: 458469
The wound healing is the principal process of tissue repair. In the heart this phenomenon is done under special circumstances, because of the constant movement of this organ. An experimental study was done in 15 dogs. By left anterolateral thoracotomy the free left ventricular wall was incised. This incision was done 1 cm long and 3 mm deep and afterwards it was repaired with silk (Group I) and with polydioxanone (Group II). The wound was allowed to heal during 5 weeks, then the scar area was analyzed by light microscope with Masson and HE technics. The results showed the presence of lymphocytes in the scar tissue of group II (p = 0.04).

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