Clinical and electrophysiological studies on posterior retinitis pigmentosa
Sakanaka, S.; Murayama, K.; Adachi, E.
Nippon Ganka Gakkai Zasshi 100(1): 50-54
1996
ISSN/ISBN: 0029-0203 PMID: 8644529 Document Number: 458133
On the basis of fundus appearance and angiographic fundus pictures, 48 cases of posterior retinitis pigmentosa were divided into pericentral type (20 cases), perimacullar type (21 cases), and macullar type (7 cases). We compared the 3 groups clinically and electrophysiologically. Visual acuity and visual field were progressively deteriorated in half of the cases of pericentral type two years after the initial visit. The waveform of flash electroretinogram (ERG) was negative in the pericentral type, subnormal in the perimacullar type, and normal in the macullar type. These ERG findings suggest that the rod function was more severely damaged in the pericentral type than in the other types. Contrary to the ERG findings, the pattern-evoked cortical potential was normal in the pericentral type, and we assumed there is less damage of the foveal function in the pericentral type.