Combination therapy with irinotecan and CBDCA for patients in terminal stage of ovarian carcinoma
Kajino, T.; Higuchi, M.; Hata, K.; Shibata, N.
Gan to Kagaku Ryoho. Cancer and ChemoTherapy 23(1): 115-117
1996
ISSN/ISBN: 0385-0684 PMID: 8546461 Document Number: 457764
Combination chemotherapy with irinotecan and CBDCA was performed for two patients in the terminal stage of ovarian carcinoma. Every week, 75 mg.m-2 of irinotecan and 75-100 mg.m-2 of CBD CA were intravenously administered. Both patients showed a partial response. Diarrhea was not a characteristic side effect of irinotecan in this case. Dose limiting factors were leucopenia and thrombocytopenia.
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