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Smoking and pregnancy: search for a correlation between cotininemia and Doppler findings

Lymperopoulou, A.; Hainaut, F.; Crimail, P.; Durand, J.L.; Locatelli, C.; Maison, C.

Journal de Gynecologie Obstetrique et Biologie de la Reproduction 25(8): 824-827

1996

ISSN/ISBN: 0368-2315
PMID: 9026511
Document Number: 457509
Objective: To search for a possible correlation between an effective marker of smoking and uterine and placental resistance during pregnancy. Study design: A prospective study was conducted at the Intercommunal Hospital Center of Montreuil, France: 81 healthy pregnant women underwent uterine and placental Doppler and cotidin blood assay, the best current test for smoking. Results: This study shows a significative increase of utero-placental vascular resistances according with increased cotidine levels. Conclusions: The previously observed association between smoking and perinatal events most likely involves vascular resistance of uterus and placenta.

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