Effectiveness of formula ophiopogoins in the treatment of xerostomia and pharyngoxerosis
Sugano, S.; Takeyama, I.; Ogino, S.; Kenmochi, M.; Kaneko, T.
Acta Oto-Laryngologica. Supplementum 522: 124-129
1996
ISSN/ISBN: 0365-5237 PMID: 8740826 Document Number: 456589
A multicenter study was carried out in 24 institutions in Kanagawa Prefecture, Japan. The subjects were 113 male and 145 female patients, ranging in age from 28 to 86 years (mean 63.7) who complained of dryness of the mouth and throat. The following illnesses were diagnosed: xerostomia and pharyngoxerosis in 161, radiation xerostomia and pharyngoxerosis in 56, chronic pharyngitis with dry mouth and throat in 22, and Sjögren's syndrome in 7. Eleven patients had other symptoms. The subjects were given a 3-g pack of granules of formula ophiopogoins three times a day before a meal. Their subjective symptoms and objective signs were examined prior to, 2, and 4 weeks after the beginning of therapy.