Increase of alpha-fetoprotein in pancreatic endocrine tumors with hepatic metastases. Apropos of 2 cases
Lesur, G.; Bergemer, A.M.; Turner, L.; Parlier, H.; Bernades, P.; Dupuy, P.
Gastroenterologie Clinique et Biologique 20(2): 204-206
1996
ISSN/ISBN: 0399-8320 PMID: 8761683 Document Number: 456377
We report two cases of metastatic non-functioning pancreatic endocrine tumour with very elevated plasma levels of alpha-fetoprotein. In these two cases, serial plasma levels of alpha-fetoprotein, initially normal, correlated well with hepatic tumour progression and were associated with fatal outcome. These results suggest that elevated plasma concentration of alpha-fetoprotein may be caused by metastatic pancreatic endocrine tumour and than alpha-fetoprotein serial measurement may be useful in prognostic evaluation.