Response to chemotherapy of brain metastases from malignant pleural mesothelioma

Colleoni, M.; Liessi, G.; Avventi, C.; Pancheri, F.; Sgarbossa, G.; Vicario, G.; Manente, P.

Tumori 82(5): 456-458

1996


ISSN/ISBN: 0300-8916
PMID: 9063523
Document Number: 456324
Brain metastases represent an uncommon complication in malignant pleural mesothelioma. A 55-year-old male suffering from malignant mesothelloma and pretreated with intracavitary chemotherapy and radiotherapy was submitted to systemic chemotherapy including lomustine, carboplatin, vinorelbine, fluorouracil and folates after diagnosis of bilateral cerebral deposits. The patient had an impressive response to chemotherapy, with complete regression of related symptoms. This case report represents the first on response to chemotherapy of brain metastases from mesothelioma. It points out that chemotherapy should be further explored in this subset of patients.

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