Infective endocarditis and occult splenic abscess caused by Brucella melitensis infection: a case report and review of the literature

Saadeh, A.M.; Abu-Farsakh, N.A.; Omari, H.Z.

Acta Cardiologica 51(3): 279-285

1996


ISSN/ISBN: 0001-5385
PMID: 8817011
Document Number: 456097
This report describes a patient with prosthetic aortic valve endocarditis caused by Brucella melitensis infection with an initial relapse after apparent recovery due to associated occult splenic abscess. In spite of a prolonged period of recovery (6 months) achieved with splenectomy and antibrucella antimicrobial therapy, a second relapse occurred and cure was achieved after replacement of the infected prosthetic valve and prolonged courses of antibrucella antimicrobial therapy. There is controversy on the optimal therapy of such cases, but this report suggests that successful management requires a combination of medical and early surgical therapy.

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