Isoforms of luteinizing hormone
Szewczuk, A.; Kochanowska, I.E.; Kurowska, E.
Postepy Higieny i Medycyny Doswiadczalnej 50(1): 9-20
1996
ISSN/ISBN: 0032-5449 PMID: 8778716 Document Number: 455849
Luteinizing hormone (LH) is a heterodimeric glycoprotein containing varied amount of sialic acid. This is a reason of numerous LH isoforms called also isohormones. The hormone isoforms were separated usually by gel electrophoresis, isoelectrofocusing or chromatofocusing. They differ in biological and immunological activity. Human and some animals LH isoforms were reviewed. Also some genetic mutants of LH are described. Problems of the human isoforms for pathology and diagnostics are presented.
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