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Translocation t (6;9;8) (p23;q34;q22) in acute myeloid leukemia: Contribution of fluorescence in situ hybridization

Van den Akker, J.; Pérot, C.; Portnoï, M.F.; Philizot, L.; Dupont, J.M.; Laporte, J.P.; Taillemite, J.L.

Annales de Genetique 38(3): 168-171

1995

ISSN/ISBN: 0003-3995
PMID: 8540689
Document Number: 453992
A complex translocation involving chromosome 6, 8 and 9 [t(6;9;8)(p23;q34;q22)] associated with other structural and numerical abnormalities was observed on bone marrow karyotype of a woman suffering with acute myeloblastic leukemia (AML2). Fluorescence in situ hybridization agreed with the conventional cytogenetic interpretation by showing that a part of chromosome 6 short arm was inserted on the rearranged chromosome 9 resulting in the t (6;9) usually encountered in AML.

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