Stewart-Treves syndrome. Immunohistochemical study apropos of 2 cases
Le Bouëdec, G.; Buono, J.P.; De Latour, M.; Toledano, E.; Vergote, T.; Dauplat, J.
Presse Medicale 24(13): 639-641
1995
ISSN/ISBN: 0755-4982 PMID: 7761364 Document Number: 453397
Two women (63 and 68 years) presented with primary angiosarcomas of the skin which had developed on an area of chronic lymphoedema after radiosurgical treatment for breast cancer 4 and 13 years earlier. Immunohistochemistry tests formally eliminated epithelial metastasis and produced evidence in favour of lymphatic or capillary vascular proliferation. Endothelial affinity for anti-factor VIII and positive tests for certain markers of intermediary filaments (actin, vimentin) confirmed the vascular and conjunctive tissue origin of the tumours.