Top Abstract Purchase Related
Home
>
Node
>
Subnode

Leptomeningeal dissemination of malignant glioma: immunohistochemical analysis of tenascin and glial fibrillary acidic protein

Higuchi, M.; Arita, N.; Ohnishi, T.; Hiraga, S.; Kusakabe, M.; Sakakura, T.; Hayakawa, T.

Clinical Neuropathology 14(4): 223-227

1995

ISSN/ISBN: 0722-5091
PMID: 8521626
Document Number: 452237
Immunohistochemical expression of tenascin (TN) and glial fibrillary acidic protein (GFAP) was investigated in 9 human malignant gliomas with leptomeningeal dissemination. In these patients intracerebral glioma tissues obtained at operation and/or autopsy displayed localized expression of TN in tumor vessels and stroma. In contrast, TN was expressed in the tumor vessels, tumor stroma, and the cytoplasm of tumor cells to a high degree throughout all the leptomeningeal tumor tissues obtained at autopsy, whereas there was much less expression of GFAP in these tissues than at the primary site. These findings suggest that TN expression and decrease of GFAP expression in glioma tissue may be involved in the development of leptomeningeal dissemination.

Document emailed within 1 workday
Secure & encrypted payments

Kałuza, J.; Adamek, D. 1990: Expression of GFAP (glial fibrillary acidic protein) antigenicity and differentiation of glioma tumor cells of astrocytic origin Folia Histochemica et Cytobiologica 28(3): 155-159
Korzhevskiĭ, D.E.; Nikoleĭshvili, M.G.; Otellin, V.A. 2005: Suppression of glial fibrillary acidic protein expression in astrocytes of the superficial glial limiting membrane after traumatic subarachnoid hemorrhage Morfologiia 127(1): 58-59
Gheuens, J.; Karcher, D.; Noppe, M.; Lowenthal, A. 1979: Comparison of the brain specific protein alpha-albumin and GFA (glial fibrillary acidic protein) Acta Neurologica Belgica 79(4): 314-321
Korzhevskiĭ, D.E.; Otellin, V.A.; Grigor'ev, I.P. 2004: Glial fibrillary acidic protein in astrocytes of the human neocortex Morfologiia 126(5): 7-10
Szymaś, J. 1986: Glial fibrillary acidic protein. a valuable tool for neuropathologic diagnosis. An introduction Zentralblatt für Allgemeine Pathologie U. Pathologische Anatomie 131(1): 3-19
Tuccari, G.; Giuffré, G.; Trombetta, C.; Barresi, G. 1993: A comparative study of glial fibrillary acidic protein (GFAP)-like immunoreactivity in the retinas of some representative vertebrates European Journal of Histochemistry: Ejh 37(3): 277
Demchenko, O.M.; Nerush, P.O. 2007: Age-related characteristics of glial fibrillary acidic protein level in the rat brain structures in pain syndrome Fiziolohichnyi Zhurnal 53(4): 43-48
Lazzari, M.; Franceschini, V.; Ciani, F. 1997: Glial fibrillary acidic protein and vimentin in radial glia of Ambystoma mexicanum and Triturus carnifex: an immunocytochemical study Journal für Hirnforschung 38(2): 187-194
Alunni, A.; Vaccari, S.; Torcia, S.; Meomartini, M.E.; Nicotra, A.; Alfei, L. 2005: Characterization of glial fibrillary acidic protein and astroglial architecture in the brain of a continuously growing fish, the rainbow trout European Journal of Histochemistry: Ejh 49(2): 157-166
O'Callaghan, J.P.; Jensen, K.F. 1992: Enhanced expression of glial fibrillary acidic protein and the cupric silver degeneration reaction can be used as sensitive and early indicators of neurotoxicity Neurotoxicology 13(1): 113-122
Sedykh, A.I.; Leshchinskaia, I.A.; Duka, T.I.; Nerush, P.A.; Pavlov, V.A. 1999: Effect of chronic emotional stress and low dose ethanol on the level of neuronal cell adhesion molecule and glial fibrillary acidic protein in rat brain Ukrains'kyi Biokhimichnyi Zhurnal 71(5): 97-103
Obukhov, S.K.; Kalashnikova, V.V.; Khalanskiĭ, A.S. 1989: Antibodies to glial fibrillary antigen as potential carriers of drugs for glial tumors Zhurnal Voprosy Neirokhirurgii Imeni N. N. Burdenko 2: 30-32
Rutka, J.T.; Giblin, J.R.; Apodaca, G.; DeArmond, S.J.; Stern, R.; Rosenblum, M.L. 1987: Inhibition of growth and induction of differentiation in a malignant human glioma cell line by normal leptomeningeal extracellular matrix proteins Cancer Research 47(13): 3515-3522
Aguirre Moreno, A.C.; Campos Peña, V.; Villeda Hernández, J.; León Rivera, I.; Montiel Arcos, E. 2011: Ganoderma lucidum reduces kainic acid-induced hippocampal neuronal damage via inflammatory cytokines and glial fibrillary acid protein expression Proceedings of the Western Pharmacology Society 54: 78-79
Kanno, T.; Nakazawa, T.; Kato, Y. 1973: Cyclic AMP and malignant glioma. II. Effects of cyclic AMP on the growth of glial tumors Rinsho Shinkeigaku 13(11): 726-731
Tökés, A.M.; Hortoványi, E.; Csordás, G.; Kulka, J.; Mózes, G.; Hatalyák, A.; Kádár, A. 1999: Immunohistochemical localisation of tenascin in invasive ductal carcinoma of the breast Anticancer Research 19(1a): 175-179
Kanno, T.; Nakazawa, T.; Kato, Y. 1972: Cyclic AMP and malignant glioma. 1. Effects of dibutyryl adenosine cyclic 3',5'-monophosphate on malignant glioma cells Rinsho Shinkeigaku 12(11): 584-595
Muir, W.; Chin, H.W.; Young, A.B.; Maruyama, Y. 1982: Proper analysis of clinical trials for malignant glioma Cancer Treatment Reports 66(1): 211-213
Tian, Y.; Li, S.; Fu, X. 1997: Immunohistochemical study of c-erbB-2 and p53 protein in breast papillomatosis and its malignant transformation Zhonghua Zhong Liu Za Zhi 19(5): 342-345
Würschmidt, F.; Bünemann, H.; Heilmann, H.P. 1995: Prognostic factors in high-grade malignant glioma. a multivariate analysis of 76 cases with postoperative radiotherapy Strahlentherapie und Onkologie: Organ der Deutschen Rontgengesellschaft . 171(6): 315-321