Cerebellar leptomeningeal astroglial heterotopia in neurofibromatosis type 1
Kato, M.; Takashima, S.; Houdou, S.; Miyahara, S.
Clinical Neuropathology 14(3): 175-178
1995
ISSN/ISBN: 0722-5091 PMID: 7671461 Document Number: 451217
Leptomeningeal astroglial heterotopia (LAH) was found in the cerebellum of 2 patients with neurofibromatosis type 1 (NF 1). This LAH was clearly and widely demonstrated with glial fibrillary acidic protein (GFAP) immunohistochemistry and was connected with parenchymal astroglial fibers. These findings suggest that NF 1 involves the dysplasia or overgrowth of astrocytes in the cerebellar leptomeninges.