Paraproteins and plasma cell dyscrasias

Karmakar, T.; Datta, U.; Varma, S.; Banerjee, C.K.; Sharma, S.; Sehgal, S.

Indian Journal of Pathology and Microbiology 38(3): 239-243

1995


ISSN/ISBN: 0377-4929
PMID: 8819653
Document Number: 449909
Serum protein electrophoresis done on 1100 patients with various diseases in one year demonstrated M-band in 31 patients. Most (87%) had the classical features of plasma cell dyscrasia (PCD), however a few had unusual presentations which are highlighted. A 22-year-old male operated for a massive tumour of the scapula clinically diagnosed as chondrosarcoma revealed plasmacytoma with amyloid on histology. Another case of kala-azar presented with features akin to that of PCD and one case had dual malignancies. Such a high incidence of PCDs with varied picture in a short time is not usually seen in other parts of this country; a fact which may be due to lack of awareness.

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