The duration of action of vecuronium in five patients after kidney transplantation--comparison with that during kidney transplantation
Takita, K.; Mashio, H.; Goda, Y.; Kawahigashi, H.; Kemmotsu, O.
Masui. Japanese Journal of Anesthesiology 44(6): 849-852
1995
ISSN/ISBN: 0021-4892 PMID: 7637164 Document Number: 449898
We compared the duration of vecuronium action in five patients after the kidney transplantation with that during kidney transplantation. After the transplantation, three patients required no hemodialysis therapy but two patients underwent hemodialysis therapy again. In all these five patients, including patients who were back to hemodialysis therapy, the durations of vecuronium action after receiving transplanted kidney were shorter than those during kidney transplantation. These shortened durations are speculated to be mainly due to excretion of vecuronium by the transplanted kidney and the effect of long term steroid therapy. However in this study the durations of vecuronium action in patients who required further hemodialysis therapy were also shorter than those during kidney transplantation. To determine whether this is a common or exceptional phenomenon, further evaluation should be needed.