Study of metabolism of T-3761 in animal
Tai, M.; Demachi, K.; Simizu, Y.
Japanese Journal of Antibiotics 48(5): 656-664
1995
ISSN/ISBN: 0368-2781 PMID: 7637200 Document Number: 449277
The metabolism of T-3761 in mouse, rat, rabbit, dog and monkey was studied. Four metabolites, other than unchanged T-3761, were detected and identified as follows: T-3761 glucuronide; T-3761M1, adduct of glucose; T-3761M2 and T-3761M3, compounds metabolized at 1-aminocyclopropyl ring. In urine of mouse, T-3761 glucuronide was mainly detected, but in urine of other animals, T-3761 was mainly detected.
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