Bone changes in postmenopausal Thai women with or without hormonal replacement therapy
Limpaphayom, K.; Taechakraichana, N.; Poshyachinda, M.; Jaisamrarn, U.
Journal of the Medical Association of Thailand 78(11): 573-577
1995
ISSN/ISBN: 0125-2208 PMID: 8576666 Document Number: 448160
Bone mass measurement was performed in 95 healthy postmenopausal women to assess the effect of hormonal replacement therapy (HRT) on bone changes. Women in the study group (51/95) received estrogen with or without progestin. The control group (44/95) did not receive any hormone regimen. The measurement was done at lumbar spines (L-1-L-4) and hip by dual energy X-ray absorptiometer at 0, 6 and 12 months. The results revealed significantly higher per cent changes of bone density of lumbar spines and hip, at 12 months, in the study group than in the control. (Study: Lumbar Spine +1.76%, Hip +3.57%; Control: Lumbar spines-2.32%, Hip + 1.32%, P lt 0.05). In conclusion, this study showed the value of hormonal replacement therapy for prevention of postmenopausal bone loss in Thai women.