Fetal fibronectin diagnosis of premature rupture of the amniotic membranes
Gu, H.; Ding, Y.; Li, Y.
Zhonghua Fu Chan Ke Za Zhi 30(9): 533-535
1995
ISSN/ISBN: 0529-567X PMID: 8556912 Document Number: 447785
To determine whether fetal fibronectin is a sensitive test for the detection of premature rupture of the amniotic membranes. Fetal fibronectin by ABC immunoblotting methods were measured in samples of cervicovaginal secretion from 80 cases with ruptured amniotic membranes (study group) and 50 cases of term pregnancy (control group A). Plasma fetal fibronectin were examined in 30 cases of normal pregnancy (control group B). The detection rate of fetal fibronectin in the women with ruptured membranes was 95.0%, While 6% in normal pregnancy. Fetal fibronectin is a sensitive test for detection of present of amniotic fluid. It can be used for diagnosis of ruptured amniotic membranes.