Effect of methacholine on mucociliary transport in bovine trachea in vitro
Mars, M.H.; Henricks, P.A.; Hajer, R.; Breukink, H.J.
American Journal of Veterinary Research 56(4): 486-488
1995
ISSN/ISBN: 0002-9645 PMID: 7785827 Document Number: 446432
A method is described to evaluate pharmacologic influence on bovine tracheal mucus transport in vitro. In this model, cholinergic agonist methacholine stimulated transport velocity. Methacholine at concentration of 10(-6)M increased velocity by 13.6%, whereas 10(-5)M increased velocity by 26%. Stimulation was inhibited by atropine.
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