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Urokinase in a premature infant: its use in a case of right atrial thrombosis secondary to catheterization of the umbilical vein

Colnaghi, C.; Cazzuffi, M.A.; Introvini, P.; Fornerone, R.; Sabatini, I.; Borin, F.; Magni, L.A.

La Pediatria Medica e Chirurgica Medical and Surgical Pediatrics 17(3): 275-277

1995

ISSN/ISBN: 0391-5387
PMID: 7567654
Document Number: 445836
Newborns with vascular catheters must be investigated by echocardiogram for intracardiac thrombosis. We report the use of urokinase to treat an asymptomatic right atrial thrombus in a 31 weeks' gestation newborn; the thrombosis occurred after placement of a catheter in the umbilical vein. We obtained a safe and successful thrombolysis using urokinase 4000 U/kg/h in continuous infusion.

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