Molecular heterogeneity of G-6-PD deficiency in Mexico
Medina, M.D.; Vaca, G.; Esparza, A.; Westwood, B.; Beutler, E.
Archives of Medical Research 26(2): 111-113
1995
ISSN/ISBN: 0188-4409 PMID: 7620274 Document Number: 444877
DNA samples from seven G-6-PD deficient Mexican mestizo patients were analyzed. Three different G-6-PD genotypes were observed: G-6-PD A-202A/376G (three patients), G-6-PD A-376G/968C (three patients) and G-6-PD Seattle844C. The present results, along with previous reports, suggest not only G-6-PD A-genotypes are relatively common but also G-6-PD deficiency seems to be heterogeneous at DNA level in Mexico.
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