Acoustic neurinomas/vestibular schwannomas. Diagnostic evidence vs. surgery
Charabi, S.; Thomsen, J.C.; Tos, M.; Mantoni, M.Y.; Charabi, B.W.; Jørgensen, B.G.; Børgesen, S.E.; Gyldensted, C.
Ugeskrift for Laeger 157(42): 5852-5857
1995
ISSN/ISBN: 0041-5782 PMID: 7483065 Document Number: 444723
+-f having vestibular schwannoma (VS) was conducted in a series of 123 patients (127 tumours), over a 20 year-period from 1973 to 1993. Mean follow up period was 3.4 years, mean annual growth rate was 3.2 mm/year. Tumour growth was observed in 90 patients (94 tumours, 74%), no growth was seen in 23 patients (23 tumours, 18%) and negative tumour growth in 10 patients (10 tumours, 8%). Surgery due to tumour growth was performed in 35 patients (35 tumours, 28%). Seven patients (seven tumours, 6%) were treated with gamma radiation and/or shunt insertion. Seven patients (6%) died of brainstem herniation induced by tumour compression. Nine patients (7%) died of non tumour related causes. Twenty-eight patients were classified as candidates for hearing preservation surgery and 21 patients (75%) lost their candidature during the observation period due to tumour growth and/or deterioration of hearing. The results may limit indications for allocation of patients with VS to the "wait and see" group.