Serum estrogens and progesterone in normal and complicated pregnancies
Panjabi, J.; Krishna, U.; Joshi, U.; Sankolli, G.M.; Rajani, U.; Devi, P.K.
Indian Journal of Medical Research 69: 954-962
1979
ISSN/ISBN: 0019-5340 PMID: 468353 Document Number: 443850
Use of serial estimations of serum estrogens (estrone + 17.beta.-estradiol) and progesterone for the evaluation of fetoplacental function was assessed during the 3rd trimester of pregnancy in 114 high risk conceptions. The hormonal levels in pregnancies at risk were compared with those obtained in normal pregnancy. Normal levels of serum estrogens during pregnancies associated with toxemia or previous obstetric problems is an indication of fetoplacental well-being; low levels of estrogens may or may not be associated with fetal jeopardy. Low levels of progesterone in serum is always associated with fetal jeopardy; however, normal level is not a definite indication of fetal well-being. In the management of Rh-isoimmunized pregnancies these parameters are not of any help, although high values were associated with severely isoimmunized cases. There is a significant correlation between estrogen values at 36-39 wk of pregnancy and the birth weight of the baby, whereas the progesterone level and birth weight are unrelated.