Genetic heterogeneity study of non-syndromic autosomal recessive sensorineural deafness within the Tunisian population
Chaabani, H.; Ben Arab, S.; Chebbi, K.
Annales de Genetique 38(3): 158-161
1995
ISSN/ISBN: 0003-3995 PMID: 8540687 Document Number: 443486
The number of loci for non-syndromic autosomal recessive sensorineural (N-SARS) deafness, was estimated within the Tunisian population and compared to that obtained in other populations. 30 deaf couples have been collected from 4 governorates (2,318,900 inhabitants) and 3 villages. Our investigations in these regions show that the percentage of congenitally deaf persons which marry each other is exceptionally low (10-30%). The number of loci for N-SARS deafness in the governorates sample was estimated at 8.3. Results could provide data for genetic counseling and facilitate our research concerning the localization of the different loci for N-SARS deafness present in Tunisian population.