Colorectal cancer: surgical prophylaxis and chemoprevention
Nugent, K.P.
Annals of the Royal College of Surgeons of England 77(5): 372-376
1995
ISSN/ISBN: 0035-8843 PMID: 7486766 Document Number: 443340
Attempts at improving outcome from colorectal cancer have recently focused on prevention. This paper describes how both surgical and chemotherapeutic intervention can cause a fall in cell proliferation, polyp regression and a decline in rectal cancer risk in patients with familial adenomatous polyposis. Other patients at high risk of colorectal cancer, or of cancers in other sites, may also have their risks modified by pharmacological intervention.